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graft-versus-host disease

Omidubicel Versus Standard Myeloablative Umbilical Cord Blood Transplantation: Results of a Phase III Randomized Study

[Blood] Investigators reported results of a Phase III trial to evaluate the efficacy of omidubicel compared to standard umbilical cord blood transplantation.

Posttransplant Cyclophosphamide as GVHD Prophylaxis for Peripheral Blood Stem Cell HLA-Mismatched Unrelated Donor Transplant

[Blood Advances] Investigators enrolled 38 patients with hematologic malignancies scheduled to undergo MMUD-HCT onto 1 of 2 conditioning strata: myeloablative using fludarabine and fractionated total body irradiation or reduced intensity with fludarabine/melphalan.

Prognostic Impacts of Peripheral Blood Erythroblasts after Single-Unit Cord Blood Transplantation

[International Journal of Laboratory Hematology] Researchers investigated the impact of erythroblasts on transplant outcomes on 225 adult patients who underwent single-unit cord blood transplantation at our single institute.

Incidence and Risk Factors of Late-Onset Hemorrhagic Cystitis after Single Umbilical Cord Blood Transplantation with Myeloablative Conditioning Regimen

[International Journal of Hematology] Scientists explored the incidence and risk factors of late-onset hemorrhagic cystitis in patients undergoing single umbilical cord blood transplantation for hematological malignancies.

Cryopreservation of Unrelated Donor Hematopoietic Stem Cells: The Right Answer for Transplantations during the COVID-19 Pandemic?

[Bone Marrow Transplantation] Investigators compared 32 patients who underwent unrelated donor (UD) hematopoietic stem cell transplantation (HSCT) using cryopreserved peripheral blood stem cells (PBSC) during the COVID-19 pandemic with 32 patients who underwent UD HSCT using fresh PBSC in the previous period.

Insights from Integrating Clinical and Preclinical Studies Advance Understanding of Graft-versus-Host Disease

[Journal of Clinical Investigation] Scientists review selected recent advances both in preclinical experimental transplantation and translational human studies, including new insights into human immunology, the microbiome, and regenerative medicine.

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