hepatic cells

[Cell Death & Disease] Researchers investigated the functional subsets of γδ T cells in hepatic fibrosis and to further explore the underlying causes and drivers of migration.

[Scientific Reports] Researchers engineered cell sheets to develop a new in vitro model of ballooned hepatocytes.

[Molecular Cancer Research] Scientists found that cancer-associated fibroblasts predominantly secreted hepatocyte growth factor (HGF) and activated MET receptor tyrosine kinase in TNBC cells.

[Biomaterials] Tthe culture and expansion of human cholangiocyte organoids in liver extracellular matrix-derived hydrogels is described. These hydrogels supported proliferation of cholangiocyte organoids and maintain the cholangiocyte-like phenotype.

[Cell Reports] To obtain a better appreciation of the molecular processes during the differentiation of iPSCs into hepatocytes, researchers employed a quantitative proteomic approach to follow the expression of 9,000 proteins, 12,000 phosphorylation sites, and 800 acetylation sites over time.

[Cell Death & Disease] Employing a combination of chimeric lineage tracing, immunofluorescence, and immunohistochemistry, the authors demonstrated that Sox9+HNF4α+ hepatocytes, generated by transition from mature hepatocytes, played an important role in the initial phase after partial hepatectomy.