hepatocytes

[Toxicology and Applied Pharmacology] The authors determined the role of the 5-HT degradation system in mitochondrial damage and apoptosis of hepatocytes.

[Acta Pharmacologica Sinica] Scientists summarize the current knowledge on the role of bile acids and the receptors in the development of nonalcoholic fatty liver disease and nnonalcoholic steatohepatitis, especially the functions of farnesoid X receptor in different tissues including liver and intestine.

[IUBMB Life] Scientists determined the epigenetic features of the HNF1A gene loci, and expression and cellular localization of HNF1A-AS1 RNA, HNF1A RNA, and HNF1A protein in colorectal cancer and normal colon epithelial cells.

[Cell Death Discovery] Researchers investigated whether long noncoding RNA SNHG1 was involved in cirrhosis by affecting hepatocyte-like cell differentiation of bone marrow-derived MSCs.

[Plant Foods For Human Nutrition] Investigators studied the metabolic effect of resveratrol around the circadian clock in order to determine more accurately the hepatic signaling pathways involved. AML-12 hepatocytes were treated with resveratrol and clock and metabolic markers were measured around the clock.

[Nature Communications] The authors suggested that KIRREL1 functioned as a feedback regulator of the mammalian Hippo pathway through sensing cell-cell interaction and recruiting SAV1 to cell-cell contact sites.