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induced pluripotent stem cells

Advances in NK Cell Production

[Cellular & Molecular Immunology] Scientists summarize the recent advances in expansion strategies with or without genetic manipulation of NK cells derived from various cellular sources.

Challenges of Organoid Research

[Annual Review of Neuroscience] Organoids hold promise for the study of atypical cellular, molecular, and genetic features that underscore neurological diseases.

Lineage Recording in Human Cerebral Organoids

[Nature Methods] Scientists established iTracer, a lineage recorder that combined reporter barcodes with inducible CRISPR–Cas9 scarring and was compatible with single-cell and spatial transcriptomics.

FUJIFILM Cellular Dynamics and PhenoVista Biosciences Announce Strategic Alliance to Improve the Drug Discovery Process

[FUJIFILM Cellular Dynamics, Inc. (GlobeNewswire, Inc.)] FUJIFILM Cellular Dynamics, Inc. and PhenoVista Biosciences announced a strategic alliance to improve the drug discovery process, by using iPSCs in screening.

Microengineered Multi-Organoid System from hiPSCs to Recapitulate Human Liver-Islet Axis in Normal and Type 2 Diabetes

[Advanced Science] Investigators developed a new microfluidic multi-organoid system that recapitulated the human liver-pancreatic islet axis in normal and disease states.

A Versatile and Robust Cell Purification System with an RNA-Only Circuit Composed of microRNA-Responsive ON and OFF Switches

[Science Advances] By designing RNA-only circuits with miRNA-ON and -OFF switch mRNAs that encoded a lethal ribonuclease, Barnase, and its inhibitor, Barstar, the authors efficiently purified specific cell types, including human iPSCs and differentiated cardiomyocytes, without flow cytometry.

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