influenza

[Proceedings of the National Academy of Sciences of the United States of America] Researchers identified and characterized an immunosuppressant protein that was highly concentrated in the submandibular salivary gland of the bat, Myotis pilosus.

[Scientific Reports] Investigators observed that the protection against influenza A virus after active vaccination with matrix protein 2 ectodomain viral antigen was lost was in Ripk3−/− mice.

[Cell Reports] Investigators found that diminished expression of a model tissue-restricted antigen gene in aged thymic stromal cells correlated with impaired clonal deletion of cognate T cells recognizing an autoantigen involved in atherosclerosis.

[Proceedings of the National Academy of Sciences of the United States of America] The authors analyzed the need for both infection and antigen presentation at the effector phase, using an in vivo sequential transfer model to time their availability.

[Nature Medicine] The author investigated influenza vaccination among adults from the Ha Nam cohort, who were purposefully selected to include 72 with and 28 without documented influenza A infection during the preceding nine years.

[Proceedings of the National Academy of Sciences of the United States of America] In the absence of IFN-γ, lung innate lymphoid cells (ILC12) from mice challenged with the A/California/04/2009 H1N1 virus, containing nonfunctional viral PB1-F2, initiated a robust IL-5 response, which also led to improved tissue integrity and increased survival.