Tag results:
insulin
Intestinal Cell News
LINC01021 Maintains Tumorigenicity by Enhancing N6-Methyladenosine Reader IMP2 Dependent Stabilization of MSX1 and JARID2: Implication in Colorectal Cancer
[Oncogene] Scientists demonstrated that oncogenic LINC021 specifically bound with the m6A “reader” IMP2 protein and enhanced the mRNA stability of MSX1 and JARID2 in an m6A regulatory manner during CRC tumorigenesis and pathogenesis.
Muscle Cell News
Muscle Protein Synthesis and Muscle/Metabolic Responses to Resistance Exercise Training in South Asian and White European Men
[Scientific Reports] In response to resistance exercise training there were no differences, between South Asians and White Europeans, muscle mass, lower body strength or insulin sensitivity.
Hepatic Cell News
Growth Hormone and Insulin-Like Growth Factor I Regulation of Nonalcoholic Fatty Liver Disease
[Journal of Clinical Endocrinology & Metabolism] Investigators focus on the potential role of growth hormone and insulin-like growth factor I in the regulation of hepatic steatosis, inflammation, and fibrosis.
Pancreatic Cell News
A Distinct Role of STING in Regulating Glucose Homeostasis through Insulin Sensitivity and Insulin Secretion
[Proceedings of the National Academy of Sciences of the United States of America] Using global stimulator of interferon genes (STING) knockout (STING−/−) and β-cell–specific STING knockout (STING-βKO) mouse models, scientists revealed a distinct role of STING in the regulation of glucose homeostasis through peripheral tissues and β-cells.
Hepatic Cell News
Small Molecule SWELL1 Complex Induction Improves Glycemic Control and Nonalcoholic Fatty Liver Disease in Murine Type 2 Diabetes
[Nature Communications] The authors showed that ICl,SWELL and SWELL1 protein were reduced in adipose and β-cells in murine and human diabetes.
Pancreatic Cell News
MYCL-Mediated Reprogramming Expands Pancreatic Insulin-Producing Cells
[Nature Metabolism] In vitro expression of Mycl provoked active replication in islet cells, even in those from aged mice.