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insulin

Impact of Insulin Producing Cells Derived from Adipose Tissue Mesenchymal Stem Cells on Testicular Dysfunction of Diabetic Rats

[Heliyon] Scientists investigated the effect of insulin-producing cells derived from adipose tissue MSCs on diabetic-induced impairments as the abnormalities of testicular tissues, oxidative stress of testes, and defects of spermatogenesis.

Adipogenic Progenitors in Different Organs: Pathophysiological Implications

[Reviews in Endocrine & Metabolic Disorders] The authors summarize some of the knowledge regarding the presence of adipose tissue in particular tissues, describing the composition of its adipogenic precursors, and the interactions responsible for the development of organ pathologies.

Influence of Obesity and Type 2 Diabetes on Calcium Handling by Skeletal Muscle: Spotlight on the Sarcoplasmic Reticulum and Mitochondria

[Frontiers in Physiology] The author considers the impact of metabolic disorders, such as obesity and type 2 diabetes, on the regulation of [Ca2+]i in skeletal muscle.

Single-Cell Analysis of the Human Pancreas in Type 2 Diabetes Using Multi-Spectral Imaging Mass Cytometry

[Cell Reports] Investigators analyzed over two million cells from 16 pancreata obtained from donors with type 2 diabetes and 13 pancreata from age-similar non-diabetic controls.

Cadmium Inhibits Signal Transducer and Activator of Transcription 6 Leading to Pancreatic β Cell Apoptosis

[Endocrine Journal] The toxic heavy metal cadmium has been proven to cause pancreatic dysfunction and lead to the development of DM. Researchers investigated the effects of cadmium on the pancreatic β cell line MIN6 and explored the underlying mechanisms.

Astragalus Polysaccharide Improve the Proliferation and Insulin Secretion of Mouse Pancreatic β Cells Induced by High Glucose and Palmitic Acid Partially through Promoting miR-136-5p...

[Bioengineered] The effect of astragalus polysaccharide on dysfunctional insulin cells was investigated to clarify whether astragalus polysaccharide could be a novel drug for type 2 diabetes mellitus treatment.

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