insulin

[Scientific Reports] Investigators showed that intramuscular injection of placental (P)-MSCs homed more towards the visceral site, restored HOMA-IR and glucose homeostasis in the WNIN/GR-Ob rats. P-MSC therapy was effective in re-establishing the dysregulated cytokines.

[Biomedicine & Pharmacotherapy] The authors highlight the interactions between mesenchymal stem cells (MSCs) and different immune cells to mediate immunomodulatory functions along with the importance of MSCs therapy for the successful islet transplantation.

[Orizuru Therapeutics, Inc.] Orizuru Therapeutics, Inc. (OZTx) announced the launch of its operations. OZTx is a research and development-driven company focusing on the development of iPSC-based regenerative medicine and the application of iPSC technology.

[Nature Reviews Endocrinology] At the time of its first clinical application 100 years ago, insulin was presented as the cure for people with diabetes mellitus. That transpired to be an overstatement, yet insulin has proven to be the lifesaver for people with type 1 diabetes mellitus and an essential therapy for many with type 2 diabetes mellitus or other forms of diabetes mellitus.

[Insulet Corporation, Inc. (BusinessWire, Inc.)] Insulet Corporation, Inc. announced FDA clearance for use of Eli Lilly and Company’s Lyumjev® 100 units/mL with Insulet’s Omnipod® Insulin Management System and Omnipod DASH® Insulin Management System.

[Nature Materials] Human IPSCs-L1 were differentiated to islet organoids and labeled with superparamagnetic iron oxide nanoparticles. The phantoms comprising of different numbers of labeled islet organoids were imaged using an magnetic particle imaging system.