insulin

[Biocon Biologics, Ltd.] Biocon Biologics Ltd. and Viatris Inc. announced that the US FDA has approved Semglee® as the first interchangeable biosimilar product under the 351(k) regulatory pathway.

[Science] Promising pharmacological advances in insulin therapy include the refinement of extremely rapid insulin analogs, alternate insulin-delivery routes, liver-selective insulins, add-on drugs that enhance insulin effect, and glucose-responsive insulin molecules.

[Journal of Biological Chemistry] Researchers investigated the effects of different doses of metformin on AQP7 expression and explored the possible mechanism of its protective effects in the pancreatic islets.

[Journal of Endocrinology] Scientists explore the timeline and history of gene discovery and how this has coincided with progress in the fields of genomics.

[The University of British Columbia] LSI Director Dr. Josef Penninger and Drs. David Long, Luigi Gnudi, and Karen Price in the UK are recipients of a UK-Canada Diabetes Research Team Grant entitled “Bridging the gap to translation by understanding and preventing diabetic vascular complications using human organoid culture” as part of the 100 Years of Insulin initiative.

[Blood] Researchers uncovered an immune-endocrine regulatory circuit that mediated cross-talk between peripheral B-cells and progenitors in the bone marrow, to balance B-lymphopoiesis in both human and mouse aging.