intestinal cells

[Nature] Researchers use single-cell RNA sequencing and antigen receptor analysis of almost half a million cells from up to 5 anatomical regions in the developing and up to 11 distinct anatomical regions in the healthy paediatric and adult human gut.

[Journal of Gastroenterology and Hepatology] Researchers investigated the role of transmembrane G-protein-coupled receptor in wound healing in the context of colonic epithelial cells in the presence of bile acids.

[Journal of Agricultural and Food Chemistry] Scientists investigated the effects of rice lipid fractions and sphingolipid glucosylceramide (GlcCer) on differentiated Caco-2 cells treated with lipopolysaccharide (LPS), in particular, they evaluated the mechanism of action of GlcCer using related substances and metabolic enzyme inhibitors.

[International Journal of Molecular Sciences] The authors summarize recent advances in the field of bile acid signaling, studies of inflamed gut microbiome, and the therapeutic potential of bile acids in the context of inflammatory bowel disease.

[Mucosal Immunology] Researchers indicated that intraepithelial CD8+ T cells were activated upon infection of intestinal epithelial cells with SARS-CoV-2, providing one possible explanation for gastrointestinal symptoms associated with COVID-19.

[Haematologica] Scientists showed that endoplasmic reticulum stress contributed to intestinal tissue injury during graft-versus-host disease and could be targeted pharmacologically.