Scientists showed that endoplasmic reticulum stress contributed to intestinal tissue injury during graft-versus-host disease and could be targeted pharmacologically.
[Haematologica]
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Haring, E., Andrieux, G., Uhl, F. M., Krausz, M., Proietti, M., Sauer, B., Esser, P. R., Martin, S. F., Pfeifer, D., Schmitt-Graeff, A., Duyster, J., Köhler, N., Grimbacher, B., Boerries, M., Aumann, K., Zeiser, R., & Apostolova, P. (2020). Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease. Haematologica. https://doi.org/10.3324/haematol.2021.278387 Cite