intestinal cells

[Cell Death Discovery] Within LPS-treated MODE-K cells, METTL3 knockdown promoted cell viability, inhibited cell apoptosis, decreased apoptotic caspase3/9 cleavage, and decreased the levels of proinflammatory cytokines and inflammatory enzymes

[Proceedings of the National Academy of Sciences of the United States of America] From an RNA interference (RNAi) screen in adult Drosophila intestinal stem cells (ISCs), researchers identified a factor, Yun, required for proliferation of normal and transformed ISCs.

[Trends in Cancer] The authors highlight the importance of stem cell/niche interactions in developing and established colorectal cancer and discuss how these can be modulated to develop novel preventive and therapeutic interventions.

[Science Immunology] Scientists linked epithelial Gasdermin D to the secretory granule exocytotic pathway and highlighted its physiological nonpyroptotic role in shaping mucosal homeostasis in the gut.

[Journal of Food Biochemistry] Researchers investigated the effect of 2'-fucosyllactose on the repair of monolayer barrier damage in Caco-2 cells by Lactobacillus rhamnosus KLDS 8001 (KLDS 8001).

[Cancer Cell International] Investigators compared the transcriptomes of nine canine cell lines derived from prostate adenocarcinoma (PAC), PAC metastasis and transitional cell carcinoma to their respective original primary tumor or metastasis tissues.