METTL3 Overexpression Aggravates LPS-Induced Cellular Inflammation in Mouse Intestinal Epithelial Cells and DSS-Induced IBD in Mice

Within LPS-treated MODE-K cells, METTL3 knockdown promoted cell viability, inhibited cell apoptosis, decreased apoptotic caspase3/9 cleavage, and decreased the levels of proinflammatory cytokines and inflammatory enzymes