intestinal epithelial cells

[Environmental Toxicology] Researchers investigated the effects of glyphosate-based herbicides on antioxidant capacity, inflammatory cytokines, and autophagy of porcine intestinal epithelial cells IPEC-J2 and its molecular mechanism.

[Acta Pharmacologica Sinica] Alcohol dehydrogenase 1C (ADH1C) was first identified as a target gene closely associated with the development of CRC by the comprehensive application of transcriptomics, proteomics, metabonomics and in silico analysis.

[Immunity] Investigators identified Sh2d6 as a signature marker for CD45+ Tuft-2 cells. Depletion of Tuft-2 cells resulted in susceptibility to bacterial infection.

[Digestive Diseases and Sciences] The authors provide novel insights into the role of chemical chaperone unfolded protein response modulators to modify endoplasmic reticulum (ER) stress levels in the pathogenesis of inflammatory bowel disease.

[Food & Function] Flow cytometry analysis of phycocyanobilin fluorescence in Caco-2 cells unveiled a similar uptake efficacy of phycocyanin and phycocyanobilin by intestinal epithelial cells.

[Cell Death Discovery] Within LPS-treated MODE-K cells, METTL3 knockdown promoted cell viability, inhibited cell apoptosis, decreased apoptotic caspase3/9 cleavage, and decreased the levels of proinflammatory cytokines and inflammatory enzymes