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leukemia

What Do We Currently Know About Chronic Myeloid Leukemia (CML) and COVID-19?

[Current Oncology Reports] The role of tyrosine kinase inhibitors as protective factors against SARS-CoV-2 infection in patients with CML should be confirmed by large-scale epidemiologic studies.

Biomarker LEPRE1 Induces Pelitinib-Specific Drug Responsiveness by Regulating ABCG2 Expression and Tumor Transition States in Human Leukemia and Lung Cancer

[Scientific Reports] Investigators discovered a mechanical correlation between leucine proline-enriched proteoglycan 1 (LEPRE1) and pelitinib drug sensitivity using in silico statistical methods and confirmed the correlation in acute myeloid leukemia and A549 lung cancer cells.

Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso

[El Paso Herald-Post] Texas Tech University Health Sciences Center (TTUHSC) El Paso has received more than a quarter-million dollars to study the proteins that contribute to disease progression and drug resistance in AML and chronic myeloid leukemia.

BeiGene Announces US FDA Acceptance of Supplemental New Drug Application for BRUKINSA (zanubrutinib) in Chronic Lymphocytic Leukemia

[BeiGene] BeiGene announced that the US FDA has accepted a supplemental new drug application or BRUKINSAĀ® for the treatment of adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.

The Role of the Atypical Chemokine Receptor CCRL2 in Myelodysplastic Syndrome and Secondary Acute Myeloid Leukemia

[Science Advances] Investigators revealed that CCRL2 was up-regulated in primitive cells from patients with myelodysplastic syndrome and secondary AML.

Glycosphingolipid-Glycan Signatures of Acute Myeloid Leukemia Cell Lines Reflect Hematopoietic Differentiation

[Journal of Proteome Research] The authors performed an in-depth glycosphingolipid (GSL) glycan analysis of 19 AML cell lines using porous graphitized carbon liquid chromatography-mass spectrometry revealing strikingly different GSL glycan profiles between the various AML cell lines.

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