Biomarker LEPRE1 Induces Pelitinib-Specific Drug Responsiveness by Regulating ABCG2 Expression and Tumor Transition States in Human Leukemia and Lung Cancer

Investigators discovered a mechanical correlation between leucine proline-enriched proteoglycan 1 (LEPRE1) and pelitinib drug sensitivity using in silico statistical methods and confirmed the correlation in acute myeloid leukemia and A549 lung cancer cells.