ATP-binding cassette

[Molecular and Cellular Biochemistry] The combined chemotherapy with methionine restriction could enhance the chemotherapeutic sensitivity of colorectal cancer stem cells by up-regulation of miR-320d to inhibit c-Myc expression

[Scientific Reports] Investigators discovered a mechanical correlation between leucine proline-enriched proteoglycan 1 (LEPRE1) and pelitinib drug sensitivity using in silico statistical methods and confirmed the correlation in acute myeloid leukemia and A549 lung cancer cells.

[Biochemical Pharmacology] Researchers summarize the major recent works on the use of antibiotics to target tumors via CSC and suggests next steps for developing this approach.

[Journal of Translational Medicine] Scientists explored the function of circular RNA nucleolar and coiled-body phosphoprotein 1 (circNOLC1) in cancer stem cells of breast cancer and the inhibitory impact of propofol on circNOLC1.

[Science Advances] The authors reported the ATP-binding cassette subfamily F member 1 (ABCF1) as a coactivator for OCT4/SOX2 critical for stem cell self-renewal.

[BMC Cancer] Investigators interupted the Trp metabolism/c-Myc loop which efficiently suppressed the drug resistance induced by TDO2, which represented a potential target in improved outcomes in drug-resistant prostatic cancer treatment.