leukocytes

[Hepatology] Scientists analyzed the immune landscapes of hypoxia-low and -high tumor regions using cytometry by time-of-flight, immunohistochemistry and transcriptomic analyses.

[Nature Reviews Gastroenterology & Hepatology] Scientists summarizes the critical mediators and mechanisms involved in immune cell trafficking in IBD and the available evidence for efficacy, safety and pharmacokinetics of sphingosine 1-phosphate receptor modulators in IBD and other immune-mediated disorders.

[Arteriosclerosis Thrombosis and Vascular Biology] Scientists discuss key findings from the latest research that give insight into the mechanisms by which clonal expansion of vascular cells contributes to disease pathology.

[NorthSea Therapeutics B.V.] NorthSea Therapeutics B.V. announced it has initiated a Phase I study with SEFA-6179 in adult subjects, targeting the initial orphan indication of the treatment of intestinal failure associated liver disease.

[Scientific Reports] Using in silico and in vitro techniques, investigators demonstrated heterogeneous expression of CD97, a leukocyte adhesion marker, in human glioblastoma.

[Molecular Biology Reports] Scientists optimized and functionally linked magnetic activated cell sorting technology as well as multiplex droplet digital PCR to their ESC screening process to achieve a greater than 60% assurance that ESC clones were correctly targeted.