lung cancer

[Bioengineered] Investigators revealed the role of CALR in lung cancer cells, indicating that highly expressed CALR proliferation at least by activation of NF-ĸB signaling pathway.

[Biochemistry and Cell Biology] The effects of small proline rich protein 1A (SPRR1A) on lung cancer cells were tested through cellular experiments and the result demonstrated that knockdown of SPRR1A could suppress proliferation and invasion capacities of tumor cells, while overexpressing SPRR1A exerted opposite effects.

[British Journal of Cancer] The authors summarize the main clinical applications of liquid biopsy in advanced NSLC, underlining both its potential and limitations from a clinically driven perspective.

[Journal of Cell Communication and Signaling] Scientists pave the way for introducing a panel of miRNAs for the prediction of tyrosine kinase inhibitors responses in lung cancer patients.

[Lancet Haematology] Researchers evaluated avatrombopag, a thrombopoietin receptor agonist that increased platelet counts, in patients with non-hematological cancer and platelet counts lower than 50 ×109 cells per L.

[Clinical Cancer Research] In a Phase I/Ib, dose-escalation/expansion study, patients with advanced/metastatic non-small cell lung cancer and 1 prior therapy received taminadenant with or without spartalizumab.