lymphocytes

[Scientific Reports] The authors investigated the relationship amongst PTEN deletion, L-asparaginase sensitivity and glucose metabolism in T cell acute lymphoblastic leukemia cells.

[Science] CD8+ T expressing inhibitory killer cell immunoglobulin-like receptors cells efficiently eliminated pathogenic gliadin-specific CD4+ T cells from celiac disease patients’ leukocytes in vitro.

[Journal of Translational Medicine] Investigators performed co-culture assays to examine expression of Th2 cytokines by triple negative breast cancer cells with and without the presence of B cells.

[International Immunopharmacology] The authors investigated the effects of S1P receptor 1 (S1P1) specific S1P analogue SEW2871, S1P1 and S1P5 specific BAF312, and non-selective FTY720 on human Th17 and Treg differentiation and IL-23-mediated signaling.

[Cancer Discovery] Scientists described the identification and characterization of INCB086550, a novel, oral, small-molecule PD-L1 inhibitor.

[Periodontology 2000] Dendritic cells consist of multiple subsets that reside in the epithelium, connective tissues, and major organs.