Tag results:
lymphocytes
Pancreatic Cell News
CCL2-Mediated Monocytes Regulate Immune Checkpoint Blockade Resistance in Pancreatic Cancer
[International Immunopharmacology] Scientists found that C-C motif chemokine ligand 2 (CCL2) recruits monocytes to and decrease CD8+ T cell infiltration in pancreatic tumors.
Cell Therapy News
Identification of Genomic Signatures in Bone Marrow Associated with Clinical Response of CD19 CAR T Cell Therapy
[Scientific Reports] In patients achieving a complete response (CR) transcriptomic profiles of bone marrow prior to lymphodepletion showed genes mainly involved in T cell activation.
Human Immunology News
Estrogen-Mediated Downregulation of HIF-1α Signaling in B Lymphocytes Influences Postmenopausal Bone Loss
[Bone Research] Using genetically modified mice and high-throughput analyses, scientists demonstrated that prolonged hypoxia-inducible factor (HIF)-1α signaling in B cells led to enhanced eceptor activator of nuclear factor kappa-Β production and osteoclast formation.
Immune Regulation News
The Development of Chiral Nanoparticles to Target NK Cells and CD8+ T Cells for Cancer Immunotherapy
[Advanced Materials] Researchers investigated the immunological effect of chiral nanomaterials as therapeutic and preventive options against tumors.
Immune Regulation News
IL-36 Cytokines Imprint a Colitogenic Phenotype on CD4+ T Helper Cells
[Mucosal Immunology] Scientists reported specifically elevated expression of IL-36α, and not IL-36β or IL-36γ in the serum of newly diagnosed, treatment naïve, pediatric inflammatory bowel diseases patients and identify T cells as primary cellular mediators of IL-36 responses in the inflamed gut.
Umbilical & Placental Cell News
Human Umbilical Cord Mesenchymal Stem Cells Alleviate the Imbalance of CD4+ T Cells via Protein Tyrosine Phosphatase Non-receptor Type 2/Signal Transducer and Activator of...
[Endocrine Journal] Human umbilical cord mesenchymal stem cells treatment significantly alleviated inflammation, reduced serum thyroid antibody levels, and decreased the ratios of IL-17α+/CD25+FOXP3+ cells and serum IFN-γ/IL-4 in experimental autoimmune thyroiditis rats.