Tag results:
lymphoid cells
Immunology of Infectious Disease News
Generation of Glucocorticoid-Resistant SARS-CoV-2 T Cells for Adoptive Cell Therapy
[Cell Host & Microbe] To assess the mechanisms contributing to protection, investigators analyzed humoral and T cell responses three weeks after a single BNT162b2 dose.
Immunology of Infectious Disease News
BATF Regulates Progenitor to Cytolytic Effector CD8+ T Cell Transition during Chronic Viral Infection
[Nature Immunology] The authors demonstrated that CX3CR1+ effector cells bear a striking similarity to short-lived effector cells during acute infection.
Extracellular Matrix News
Tumor Microenvironment-Adjusted Prognostic Implications of the KRAS Mutation Subtype in Patients with Stage III Colorectal Cancer Treated with Adjuvant FOLFOX
[Scientific Reports] Considering the effect of KRAS mutations on tumor microenvironment, investigators analyzed the prognostic significance of KRAS mutation types after adjusting for the tumor-infiltrating lymphocytes and tumor-stromal percentage statuses.
Extracellular Matrix News
Differential Integrin Adhesome Expression Defines Human NK Cell Residency and Developmental Stage
[Journal of Immunology] Scientists defined differences in cortical actin content associated with differential expression of actin regulating proteins, suggesting that differences in adhesome expression were associated with differences in cortical actin homeostasis.
Prostate Cell News
Castration-Mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression
[Nature Cancer] Scientists established a novel mechanism by which castration mediated IL-8 secretion and subsequent polymorphonuclear myeloid-derived suppressor cells infiltration.
Muscle Cell News
Single-Cell RNA-Seq Reveals Cellular Heterogeneity of Mouse Carotid Artery under Disturbed Flow
[Cell Death Discovery] Scientists investigated the heterogeneity of vascular cell populations under disturbed blood flow (d-flow). A d-flow-induced Spp1hi vascular smooth muscle cell subpopulation appeared to be endowed with osteoblast differentiation, suggesting a role in arterial stiffness.