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macrophages

In Situ Imaging for Tumor Microbiome Interactions via Imaging Mass Cytometry on Single-Cell Level

[Cytometry Part A] Researchers developed a rapid semi-quantitative method for in situ imaging of bacteria and multiplex cell phenotypes on the same solid tumor tissue sections.

Effects of Immune Cells on Intestinal Stem Cells: Prospects for Therapeutic Targets

[Stem Cell Reviews and Reports] The authors describe the effects of various immune cells on intestinal stem cells (ISCs), as well as the mechanisms underlying these effects and also highlight the remarkable role of ISCs in intestinal pathogenesis.

Tumor-Associated Macrophage Derived IL-6 Enriches Cancer Stem Cell Population and Promotes Breast Tumor Progression via Stat-3 Pathway

[Cancer Cell International] Researchers reported that macrophages, upon interaction with breast cancer cells, activated tumor promoting functions and exhibited differential expression of various proteins as shown by secretome analysis using proteomics studies.

Noncoding RNA-Mediated Macrophage and Cancer Cell Crosstalk in Hepatocellular Carcinoma

[Molecular Therapy-Oncolytics] The authors provide an update on the regulation of noncoding RNAs in the crosstalk between macrophages and tumor cells in HCC.

Reactive Gliosis in Alzheimer’s Disease: A Crucial Role for Cognitive Impairment and Memory Loss

[Metabolic Brain Disease] The authors review the mechanisms by which a reactive gliosis can induce or contribute to the development and progression of Alzheimer’s disease.

Targeting Tumor Associated Macrophages in Hepatocellular Carcinoma

[Biochemical Pharmacology] Scientists summarize what we know about tumor-associated macrophages (TAMs) and HCC, discussing the roles of TAMs in HCC development and the possible approaches for TAMs-targeted therapy as potential targets for HCC treatment.

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