macrophages

[British Journal of Anaesthesia] Scientists quantified ex vivo neutrophil extracellular traps (NET) induction in septic humans and murine models of sepsis to identify signalling pathways that may be modulated to improve outcome in human sepsis.

[Nature Communications] Scientists performd a comprehensive analysis of the plasma proteome of more than 1400 proteins in children with SARS-CoV-2. They showed that protein signatures demonstrated overlap between multi-system inflammatory syndrome in children, and the inflammatory syndromes macrophage activation syndrome and thrombotic microangiopathy.

[Nature Communications] Researchers indicated that KLF4 played opposing roles in platelet-derived growth factor receptor-β+ cells and α-smooth muscle actin+ cells and highlighted the importance of further studies of interactions between distinct mesenchymal cell types.

[Molecular Immunology] Researchers investigated whether Omarigliptin possessed a beneficial effect against LPS-induced injuries in human BEAS-2B bronchial epithelial cells.

[Journal of Clinical Investigation] Investigators found that BMP9/BMP10-ALK1 signaling controlled the identity and self-renewal of Kupffer cells through a Smad4-dependent pathway.

[Oncogene] Scientists found that the 18fluoro-deoxyglucose positron emission tomography/computed tomography-based markers were positively associated with the expression of programmed cell death ligand 1, pyruvate kinase M2, both of which indicate poor prognosis in patients with pancreatic ductal adenocarcinoma.