macrophages

[Frontiers in Genetics] Recent studies focus on bulk and single cell transcriptomics of the island macrophage during adult steady-state erythropoiesis and embryonic erythropoiesis.

[Seminars in Immunology] Scientists summarize current insights into the mechanisms of macrophage-mediated host defense and repair during helminth infection and highlight recent progress on the immune regulatory crosstalk between macrophages and helminth parasites.

[Cancer Immunology Research] Transcriptome analysis revealed that B7-H3 was highly expressed in PD-L1-low, non-immunoreactive high-grade serous ovarian cancer tumors, and its expression negatively correlated with an IFNγ signature, which reflected the tumor immune-reactivity.

[Journal of Ethnopharmacology] The authors investigated the wound healing potential of okra fruit by in vitro and in vivo experimental models. The biocompatibility of the gel formulations prepared with the best performing extract were evaluated by human Epiderm™ reconstituted skin irritation test model.

[Cellular & Molecular Immunology] Agonist-induced stimulator of interferon genes (STING) signaling activation in macrophages was revealed to inhibit covalently closed circular DNA-mediated transcription and hepatitis B virus (HBV) replication via epigenetic modification in hepatocytes.

[NPG Asia Materials] 3D printed macrophage exosomes scaffolds, exhibiting a predefined structure and persistent release of exosomes, displayed distinct immunomodulatory effects and improved osteogenesis/angiogenesis.