macrophages

[Arteriosclerosis Thrombosis and Vascular Biology] In the mouse aortocaval fistula model, anti-PD-L1 antibody was given to inhibit PD-L1 activity during arteriovenous fistulae maturation.

[Cancer Cell] The authors defined distinct features of the bone marrow (BM) microenvironment and analyzed single cells from bone metastatic prostate tumors, involved BM, uninvolved BM, and BM from cancer-free, orthopedic patients, and healthy individuals.

[Cancer Cell] Investigators demonstrated that high levels of baseline CXCL13+ T cells are linked to the proinflammatory features of macrophages and can predict effective responses to the combination therapy.

[Frontiers in Imm] The authors demonstrated that Mycobacterium tuberculosis infection triggered a time-dependent reduction in the expression of focal adhesion kinase in human macrophages.

[Molecular Therapy] Scientists revealed that MSC-derived exosomes resided specifically in the injured kidney and delivered miRNA-34c-5p to reduce cellular activation and renal interstitial fibrosis by inhibiting core fucosylation.

[Nature Communications] In obesity, macrophages drive a low-grade systemic inflammation and insulin resistance. Scientists reported an unexpected location and function of NOC4L, which was preferentially expressed in human and mouse macrophages.