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mammary cells

A Bioinspired Redox-Modulating Copper(ii)–Macrocyclic Complex Bearing Non-steroidal Anti-inflammatory Drugs with Anti-Cancer Stem Cell Activity

[Dalton Transactions] Investigators reported a biologically stable copper(II) complex based on the active site of Type I copper electron transport proteins.

Cysteine-Rich Domain of Type III Collagen N-Propeptide Inhibits Fibroblast Activation by Attenuating Tgfβ Signaling

[Matrix Biology] Scientists defined type III Collagen as a suppressor of scar formation and desmoplasia through its effects, in part, on myofibroblasts.

Engineering Tumor Constructs to Study Matrix-Dependent Angiogenic Signaling of Breast Cancer Cells

[Biotechnology Progress] Scientists reported the development of an in vitro 3D breast cancer model to investigate the effect of stromal crosslinking and consequent, stiffening on the angiogenic activity of cancer cells.

Procr Functions as a Signaling Receptor and Is Essential for the Maintenance and Self-Renewal of Mammary Stem Cells

[Cell Reports] By conditional knockout in mammary stem cells, investigators demonstrated that protein C receptor (Procr) is essential for mammary gland development and homeostasis.

Label-Free Enrichment of MCF7 Breast Cancer Cells from Leukocytes Using Continuous Flow Dielectrophoresis

[Electrophoresis] Scientists presented a continuous flow, antibody-free dielectrophoresis-based microfluidic device to concentrate MCF7 breast cancer cells, a well-established circulating tumor cells model, in the presence of leukocytes extracted from human blood samples.

New Advances in Targeted Therapy of HER2-Negative Breast Cancer

[Frontiers in Oncology] The authors describe the potential targets that may be used for breast cancer treatment from the aspects of PI3K/AKT signaling pathway, DDR, angiogenesis, the cell cycle, breast cancer stem cells, etc

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