mammary stem cells

[Scientific Reports] When investigators analyzed only the genes that were differentially expressed in the stem cell enriched fraction, clusters of downregulated genes were related to proliferation, while among the upregulated expression, cluster of genes related to cell adhesion, migration and cytoskeleton organization were observed.

[Scientific Reports] Scientists provided evidence that TGF-β disrupted the lineage commitment and promoted the accumulation of tumor-initiating cells in pre-neoplastic cells.