mass spectrometry

[Journal of Proteome Research] The authors performed an in-depth glycosphingolipid (GSL) glycan analysis of 19 AML cell lines using porous graphitized carbon liquid chromatography-mass spectrometry revealing strikingly different GSL glycan profiles between the various AML cell lines.

[Leukemia] To interrogate the effect of protein expression alterations in AML, researchers performed a quantitative mass spectrometry in parallel with RNAseq analysis using AML mouse models.

[Molecular Therapy Oncolytics] The combination of reovirus and NAD+ depletion achieved greater antitumor effects in KMS12 tumors in vivo and patient-derived CD138+ multiple myeloma cells.

[Scientific Reports] The authors performed mass spectrometry analysis of APOBEC3B (A3B)-interacting proteins from nuclear extracts of myeloma cell lines and identified 30 putative interacting proteins.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers described the identification of vimentin, an intermediate filament protein widely expressed in cells of mesenchymal origin, as an important attachment factor for SARS-CoV-2 on human endothelial cells.

[Nature Protocols] Researchers developed a protocol to visualize and quantify the spatiotemporal evolution of newly synthesized and deposited matrix by cells that are either cultured atop or embedded within biomaterial systems.