mesenchymal stem cells

[Biotechnology Journal] Scientists demonstrated a simple method to perform layer by layer assembly on microcarriers to create multilayers of heparin and collagen and further demonstrated that these multilayers had a positive effect on human MSC viability after 48 hours of culture.

[Stem Cell Research & Therapy] The authors summarize the current approaches of MSC pre-activation and further classify, analyzed the scientific principles and main characteristics of these manipulations, and describe the pros and cons of individual pre-activation strategies.

[Acta Pharmacologica Sinica] Researchers investigated the effects of rapamycin on the proangiogenic ability of senescent human umbilical cord mesenchymal stem cells.

[Future Science OA] Wistar rats were randomly selected to receive an intravenous injection of human umbilical cord-MSC or the vehicle one hour after a severe Intracerebral hemorrhage.

[Experimental and Molecular Medicine] To identify MSC subpopulations and clarify their relationships, scientists performed cell mapping of bone marrow-derived MSCs through single-cell RNA sequencing.

[Bone Research] Scientists reported that circular RNA (circRNA) Stag1 was a critical osteoporosis-related circRNA that showed significantly downregulated expression in osteoporotic bone marrow MSCs and clinical bone tissue samples from patients with osteoporosis.