mesenchymal stem cells

[Journal of Molecular Neuroscience] After stimulation with Zeb2/Axin2-enriched BMSC exosomes, the spatial memory and nerve function of MCAO rats showed marked recovery. The number of neurons was increased in the subventricular zone, hippocampus, and cortex area, while the expression of nerve growth factors was upregulated.

[Journal of Cellular Biochemistry] Coinjections of endothelial progenitor cells + mesenchymal stem cells significantly enhanced the survival rate of lipopolysaccharide-induced mice, decreased concentrations of pro-inflammatory cytokines, and increased the level of anti-inflammatory cytokine.

[Cell Death Discovery] Investigators explored the repair effect of human umbilical cord MSCs-derived extracellular vesicles on spinal cord injury.

[Photodiagnosis and Photodynamic Therapy] Scientists explored whether the combination of MSCs and 5-aminolevulinic acid photodynamic therapy will exert a more advanced curative effect on diabetic ulcer.

[Stem Cell Research] Scientists generated an induced pluripotent stem cells (iPSC) line from bone marrow-MSCs employing a non-integrating episomal vector. The generated iPSCs expressed pluripotency markers, showed a normal karyotype, and exhibited the potential for in vitro differentiation into three germ layers.

[Journal of Pharmacology and Experimental Therapeutics] A qPCR analytical method with matrix effect was developed to track the biodistribution of human mesenchymal stem cells in normal and Con A induced liver injury mice.