mesenchymal stem cells

[Communications Biology] The authors demonstrated that astrocyte-like-cells could be derived from adult human gingiva mesenchymal stem cells and used for Tissue-Engineered-rostral migratory stream fabrication.

[Scientific Reports] Researchers showed an effective method for transplantation of adipose-derived MSCs spheroids onto skin wounds in order to efficiently cure refractory ulcers.

[Signal Transduction and Targeted Therapy] The authors revealed that dead MSCs alone in the therapeutic stem cell preparation or the apoptotic cells induced in vivo may exert the same immunomodulatory property as the “living MSCs preparation” through releasing phosphatidylserine, which was further recognized by Mer tyrosine kinase and participated in modulating immune cells.

[Advanced Science] Investigators proposed an approach based on triboelectric stimulation to rejuvenate senescent bone marrow MSCs by fabricating a pulsed triboelectric nanogenerator that could produce stable pulsed current output unaffected by the triggered frequency.

[Stem Cell Research & Therapy] Researchers compared the cytoprotection between peritoneal dialysis (PD) effluent-derived MSCs and umbilical cord-derived MSCs in the treatment of both peritoneal membrane and kidney injury in uremic rats with chronic PD.

[Stem Cell Research & Therapy] Scientists investigated the effects of storage solutions and heterogeneity on the behavior of MSCs in vitro and in vivo.