monocytes

[iScience] The authors hypothesized that viral mimic-priming improved mesnchymal stem cells' abilities to rebalance the dysregulated immune responses in COVID-19.

[Scientific Reports] Researchers investigated the toxicity of different phosphate compounds to TNBCs, particularly, MDA-MB-231, and compared it to that of human monocytes, THP-1.

[Cancer Immunology Immunotherapy] In an in vitro study using lung cancer cell lines and human monocyte-derived macrophages, the conditioned medium from cancer cells was found to up-regulate programmed cell death-1 ligand 1 expression on macrophages via STAT3 activation.

[Proceedings of the National Academy of Sciences of the United States of America] Investigators found that targeting colony stimulating factor 1 (CSF-1) with neutralizing antibody halted ongoing encephalomyelitis, with efficacy superior to colony CSF-1 receptor inhibitor BLZ945, whereas IL-34 neutralization had no effect, suggesting that pathogenic myeloid cells were maintained by CSF-1.

[Scientific Reports] The authors investigated whether local delivery of adeno-associated viral (AAV) vectors expressing oxidation-resistant wild type apolipoprotein A1 (apoA1) preserved apoA1 functionality.

[Nature Communications] The authors reported that vaccinia C7 was a crucial virulence factor that blocked activation of the transcription factor IRF3.