[Nature Cell Biology] Investigators observed that initiation of differentiation in iPSCs and ESCs triggered widespread apoptosis, followed by a synchronous epithelial–mesenchymal transition.
[Cell Stem Cell] Investigators reported a chemical cocktail of five small molecules that promoted adult cardiomyocyte proliferation and heart regeneration.
[Cell Death Discovery] Scientists confirmed that LPS significantly enhanced the expression of islet cell autoantigen 69 (ICA69) in wild-type mice, macrophages, and cardiomyocytes.
[Cellular and Molecular Life Sciences] Researchers developed a multifactor-based protocol that combined adenovector-mediated MYOD expression, small molecule inhibitor and growth factor treatment, and electrical pulse stimulation to efficiently reprogram different types of human-derived multipotent stem cells into physiologically functional skeletal muscle cells.
[Kaohsiung Journal of Medical Sciences] Scientists deciphered the role of the lncRNA antisense noncoding RNA in the INK4 locus in airway smooth muscle cell proliferation, migration and extracellular matrix deposition.
[Journal of Cardiovascular Pharmacology] Researchers investigated the effect of circLDLR on the proliferation and apoptosis of vascular smooth muscle cells in coronary artery disease and its regulatory mechanism.