muscle cells

[Biophysical Journal] Transient receptor potential vanilloid 4 (TRPV4) enabled endothelial cells, smooth muscle cells, and perivascular neurons, to integrate hemodynamic forces to regulate systemic blood pressure.

[Nature Cardiovascular Research] Researchers presented the transcriptional response of human cardiomyocytes to pressure overload caused by aortic valve stenosis and described major alterations in cardiac cellular crosstalk.

[Cellular Signalling] Researchers found that PH domain leucine-rich repeat protein phosphatase1 (PHLPP1) deficiency enhanced Thr163 phosphorylation of Mcl-1, inhibited Mcl-1 degradation and maintained Mcl-1 protein expression level in myocardium and cardiomyocytes upon myocardial infarction or Dox treatment.

[Pharmacological Research] Scientists found that the iron level, ferroptosis-related molecules TFR, HOMX1, ferritin and the lipid peroxidation product 4-hydroxynonenal were increased in the aorta of aortic dissection.

[Experimental Cell Research] Researchers established an in vitro VC model of vascular smooth muscle cells (VSMCs) and an adenine-induced CKD mouse model.

[American Journal of Respiratory Cell and Molecular Biology] A long non-coding RNA attenuated by platelet-derived growth factor BB was identified and its functional roles were investigated in vitro and in vivo.