myeloid cells

[Cell Death & Disease] Scientists demonstrated that fibroblast growth factor-binding protein 1 was dramatically upregulated in airway epithelial cell lines treated by poly-L-arginine, a mimic of major basic protein.

[Cell Research] Single-cell transcriptomics revealed three transcriptionally heterogeneous hematopoietic stem cell and multipotent progenitor subsets, among which a CD93-enriched subset exhibited enhanced stem cell properties.

[Molecular Immunology] Investigators focused on the potential involvement and mechanism of LINC00337 in breast cancer (BCa). High-expressed LINC00337 accelerated viability and proliferation of BCa cells, improved the resistance of BCa cells to paclitaxel, and accelerated tumor growth.

[Cell Reports] Through a combination of in vitro assays, mouse models, and intravital imaging, scientists found that S. aureus immune evasion in skin was controlled by a cascade composed of the ArlRS two-component regulatory system and its downstream effector, MgrA.

[EMBO Journal] Investigators showed that the nucleocapsid of SARS-CoV-2 inhibited host pyroptosis by blocking Gasdermin D cleavage. SARS-CoV-2-infected monocytes showed enhanced cellular interleukin 1b (IL-1b) expression, but reduced IL-1b secretion.

[EBiomedicine] The authors aimed to decipher SARS-CoV-2 infected cell types, the consequent host immune response and their interplay in lung of COVID-19 patients.