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myocardial infarction

Muscle Cell News

A Small-Molecule Cocktail Promotes Mammalian Cardiomyocyte Proliferation and Heart Regeneration

[Cell Stem Cell] Investigators reported a chemical cocktail of five small molecules that promoted adult cardiomyocyte proliferation and heart regeneration.
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Muscle Cell News

LncRNA FAF Attenuates Hypoxia/Ischaemia-Induced Pyroptosis via the miR-185-5p/PAK2 Axis in Cardiomyocytes

[Journal of Cellular and Molecular Medicine] Investigators explored the antipyroptotic effects of long noncoding RNA (lncRNA) FGF9-associated factor (FAF) in acute myocardial infarction.
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Human Immunology News

Monocyte Subpopulation Profiling Indicates CDK6-Derived Cell Differentiation and Identifies Subpopulation-Specific miRNA Expression Sets in Acute and Stable Coronary Artery Disease

[Scientific Reports] Investigators characterized monocyte subsets in controls and disease phenotypes of coronary artery disease and mmyocardial infarction patients using flow cytometry and miRNA and mRNA expression profiling using RNA sequencing.
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Mesenchymal Cell News

EZH2 Mitigates the Cardioprotective Effects of Mesenchymal Stem Cell-Secreted Exosomes against Infarction via HMGA2-Mediated PI3K/AKT Signaling

[BMC Cardiovascular Disorders] Investigators probed the therapeutic effects of MSC-derived exosomes on myocardial fibrosis after myocardial infarction and possible mechanisms.
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Muscle Cell News

Sox9 Promotes Cardiomyocyte Apoptosis after Acute Myocardial Infarction by Promoting miR-223-3p and Inhibiting MEF2C

[Molecular Biotechnology] Researchers probe the role of Sox9 in cardiomyocyte apoptosis after acute myocardial infarction (AMI). AMI cell model was established in AC16 cells by hypoxia treatment.
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Umbilical & Placental Cell News

Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Loaded with miR-223 Ameliorate Myocardial Infarction through P53/S100A9 Axis

[Genomics] Scientists explored the mechanism of human umbilical cord mesenchymal stem cells-derived extracellular vesicles loaded with miR-223 on myocardial infarction. Inflammation, cell biological functions, and fibrosis in vitro were measured.
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