neural cells

[Proceedings of the National Academy of Sciences of the United States of America] Researchers found that slowing the activation of K+ current can increase the Na+ influx rate, and the effect of minimizing the overlapped between Na+ and K+ currents on spike propagation resilience depended on complex interactions among diameter, myelination, and the Na/K pump density.

[Cell Reports] Scientists assessed medial prefrontal cortex and visual cortex astrocyte and whole-tissue gene expression changes in mice following peripherally induced neuroinflammation triggered by a systemic bacterial endotoxin, lipopolysaccharide, which produced sickness-related behaviors, including anhedonia.

[Heliyon] Scientists investigated the effects of Orengedokuto on inflammatory molecule induction in BV-2 microglial cells using real-time RT-PCR and ELISA.

[Cell Metabolism] The paradigm of this biological feature is the astrocyte-neuron couple, in which the glycolytic metabolism of astrocytes contrasts with the mitochondrial oxidative activity of neurons.

[Stem Cell Reports] Investigators used single-cell transcriptomics to dissect the cell states that emerge during NGN2 overexpression across a time course from pluripotency to neuron functional maturation.

[Scientific Reports] Scientists observed that during normal cerebellar development, phosphorylated CREB was selectively expressed in differentiating cerebellar granule neuron progenitor (CGNP) cells.