neurons

[Cell Death Discovery] Researchers investigated the physiological mechanisms by which extracellular vesicle-encapsulated miR-181a–2–3p derived from MSCs might mediate oxidative stress in Parkinson’s disease

[Frontiers in Cellular Neuroscience] Using a rat cervical hemicontusion model, investigators evaluated the survival and integration of human iPSC-derived spinal motor neurons and oligodendrocyte progenitor cells.

[Nature Communications] Scientists integrated human genetics with transcriptomic data from differentiation of human ESCs into cortical excitatory neurons.

[Nature] Investigators used brain organoids to show that although sex chromosomal complement had no observable effect on neurogenesis, sex steroids—namely androgens—led to increased proliferation of cortical progenitors and an increased neurogenic pool.

[Cell Reports] Scientists showed that the neuronal retromer could regulate Alzheimer's disease (AD)-associated pathologies in two of AD's principal cell types, which strengthened the link, and clarified the mechanism, between endosomal trafficking and late-onset sporadic AD.

[Molecular Neurobiology] The authors discuss multiple pathophysiological aspects of white matter injury along with glial dynamics, and the pharmacotherapies including recent insights into the application of MSCs as therapeutic modality in treating white matter injury.