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neurons

Human and Mouse Trigeminal Ganglia Cell Atlas Implicates Multiple Cell Types in Migraine

[Neuron] Investigators developed a cell atlas in which human and mouse trigeminal ganglia were transcriptionally and epigenomically profiled at single-cell resolution.

Oleic Acid Is an Endogenous Ligand of TLX/NR2E1 That Triggers Hippocampal Neurogenesis

[Proceedings of the National Academy of Sciences of the United States of America] Investigators showed that oleic acid was critical for neural stem cell survival and demonstrated that it binds to the nuclear receptor TLX to convert it from a transcriptional repressor to a transcriptional activator of cell-cycle and neurogenesis genes.

Comparative Microelectrode Array Data of the Functional Development of hPSC-Derived and Rat Neuronal Networks

[Scientific Data] Researchers presented a dataset of microelectrode array recordings from hPSC-derived and rat embryonic cortical neurons during their in vitro maturation.

Analysis of Mitochondrial Dysfunction by Microplate Reader in hiPSC-Derived Neuronal Cell Models of Neurodegenerative Disorders

[Methods in Molecular Biology] The authors describe high-throughput analysis of crucial parameters related to mitochondrial function in hiPSC-derived neurons.

Human Forebrain Organoids Reveal Connections between Valproic Acid Exposure and Autism Risk

[Translational Psychiatry] Scientists used human forebrain organoids, in vitro derived 3D cell cultures that recapitulated key human brain developmental features.

Production of Human Spinal-Cord Organoids Recapitulating Neural-Tube Morphogenesis

[Nature Biomedical Engineering] Investigators reported a 3D culture system and protocol for the production of human spinal-cord-like organoids recapitulating the neurulation-like tube-forming morphogenesis of the early spinal cord.

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