neutrophils

[Cell Death Discovery] Scientists evaluated the effect of imipenem and ceftriaxone on neutrophil extracellular traps (NETs) formation in vitro and examined the role of reactive oxygen species.

[Molecular Pharmaceutics] Investigators used an in vitro peristaltic pump setup that mimiced pulsatile blood flow to determine if immune cells took up particles under constant fluidic flow.

[Journal of Experimental Medicine] Researchers observed that neutrophil DREAM repressed expression of A20, a negative regulator of NF-κB activity, and enhanced expression of pro-inflammatory molecules and phosphorylation of IκB kinase after TNF-α stimulation.

[PLoS One] Investigators established a model for interleukin 1β (IL-1β)-induced dermatitis and investigated mitogen-activated protein kinase signaling pathways in IL-1β-induced interleukin 8 (IL-8) expression.

[Scientific Reports] Investigators reported a role for excessive neutrophil extracellular trap formation induced by uremic serum on endothelial cell injury.

[Autophagy] Researchers identified endothelial cell autophagy as a negative regulator of neutrophil diapedesis in acute physiological inflammation.