neutrophils

[PLoS Pathogens] Investigators assessed the influence of COVID-19 plasma hypercytokinemia on the functional responses of myeloid immune cells upon bacterial challenges from acute-phase COVID-19 patients and their corresponding recovery (rec)-phase.

[Experimental and Molecular Medicine] Investigators found that CU06-1004, as a vascular leakage blocker, could improve cardiac function by inhibiting cardiac microvascular endothelial cells' hyperpermeability and subsequently reducing the neutrophil’s plugging and infiltration in infarcted hearts.

[American Journal of Hematology] Researchers evaluated 7861 patients with hematologic malignancies who received either a cord blood transplantr without anti-thymocyte globulin (ATG) or an HLA 1-3 antigen–mismatched related donor peripheral blood stem-cell transplantation using low-dose ATG.

[Cell] Researchers identified highly activated, CD16+ T cells with increased cytotoxic functions in severe COVID-19.

[Acta Biomaterialia] Scientists assessed the local and systemic innate immune responses to implantation of biphasic calcium phosphate biomaterial alone, or with bone marrow derived MSC, in critical-sized calvarial bone defects of Lewis rats.

[Seminars in Immunology] The authors summarize and detail clinical and experimental evidence for, and underlying mechanisms of, the dual impact of neutrophils' functions, both supporting and inhibiting cancer development.