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NF-κB
Dermal Cell News
CircOAS3 Regulates Keratinocyte Proliferation and Psoriatic Inflammation by Interacting with Hsc70 via the JNK/STAT3/NF-κB Signaling Pathway
[Inflammation] Investigators found that circular RNA OAS3 (circOAS3) expression was significantly upregulated in both psoriatic tissues and M5-induced keratinocytes.
Mesenchymal Cell News
Anti-Inflammatory Effects of Mesenchymal Stem Cell-Conditioned Media Inhibited Macrophages Activation In Vitro
[Scientific Reports] Scientists investigated the anti-inflammatory effects of MSCs on lipopolysaccharide-stimulated macrophages and the subsequent downregulation of their inflammatory mediators.
Pulmonary Cell News
The Arginine Methyltransferase PRMT7 Promotes Extravasation of Monocytes Resulting in Tissue Injury in COPD
[Nature Communications] Scientists showed that in COPD patients, protein arginine methyltransferase 7 (PRMT7) expression was elevated in the lung tissue and localized to the macrophages.
Dermal Cell News
MiR-378a Regulates Keratinocyte Responsiveness to IL-17A in Psoriasis
[British Journal of Dermatology] Investigators showed that microRNA-378a (miR-378a) was induced by IL-17A in keratinocytes through NF-κB, C/EBP-β and IκBζ, and was overexpressed in psoriasis epidermis.
Prostate Cell News
Inflammatory Molecules Facilitate the Development of Docetaxel-Resistant Prostate Cancer Cells In Vitro and In Vivo
[Fundamental & Clinical Pharmacology] The changes in gene expression profiles of multidrug resistant prostate cancer cells that were established in response to docetaxel were determined using microarray analysis.
Pulmonary Cell News
Povidone Iodine Suppresses LPS-Induced Inflammation by Inhibiting TLR4/MyD88 Formation in Airway Epithelial Cells
[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.