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NF-κB

CircOAS3 Regulates Keratinocyte Proliferation and Psoriatic Inflammation by Interacting with Hsc70 via the JNK/STAT3/NF-κB Signaling Pathway

[Inflammation] Investigators found that circular RNA OAS3 (circOAS3) expression was significantly upregulated in both psoriatic tissues and M5-induced keratinocytes.

Anti-Inflammatory Effects of Mesenchymal Stem Cell-Conditioned Media Inhibited Macrophages Activation In Vitro

[Scientific Reports] Scientists investigated the anti-inflammatory effects of MSCs on lipopolysaccharide-stimulated macrophages and the subsequent downregulation of their inflammatory mediators.

The Arginine Methyltransferase PRMT7 Promotes Extravasation of Monocytes Resulting in Tissue Injury in COPD

[Nature Communications] Scientists showed that in COPD patients, protein arginine methyltransferase 7 (PRMT7) expression was elevated in the lung tissue and localized to the macrophages.

MiR-378a Regulates Keratinocyte Responsiveness to IL-17A in Psoriasis

[British Journal of Dermatology] Investigators showed that microRNA-378a (miR-378a) was induced by IL-17A in keratinocytes through NF-κB, C/EBP-β and IκBζ, and was overexpressed in psoriasis epidermis.

Inflammatory Molecules Facilitate the Development of Docetaxel-Resistant Prostate Cancer Cells In Vitro and In Vivo

[Fundamental & Clinical Pharmacology] The changes in gene expression profiles of multidrug resistant prostate cancer cells that were established in response to docetaxel were determined using microarray analysis.

Povidone Iodine Suppresses LPS-Induced Inflammation by Inhibiting TLR4/MyD88 Formation in Airway Epithelial Cells

[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.

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