NF-κB

[Cell Death & Disease] After myocardial ischemia reperfusion surgery, IL-1R2 expression was significantly increased in heart of wild-type mice.

[British Journal of Nutrition] Researchers assessed the effect of citrus flavonoids and their intestinal metabolites on immune-mediated barrier disruption in an in vitro co-culture model.

[Journal of Hepatology] The authors reported that HCV infection was favored by heparanase-1 (HPSE), and upregulated HPSE expression and secretion, which may have resulted in potentially pathogenic alterations of the extracellular matrix.

[Cellular and Molecular Life Sciences] Scientists showed that the signaling protein WNT3A counteracted the induction of paracrine senescence in cultured human adult MSCs.

[Communications Biology] Researchers showed that norepinephrine secretion from intrinsic cardiac adrenergic cells was increased through activation of Toll-like receptor 4 to aggravate myocardial TNF-α production and dysfunction by lipopolysaccharide (LPS).

[International Journal of Biological Macromolecules] Researchers investigated systematically the roles of a proteoglycan from Ganoderma lucidum in protection and repair of pancreatic β-cells against oxidative stress-induced injury and apoptosis on molecular, cellular and animal basis.