osteogenic differentiation

[NPJ Regenerative Medicine] Researchers found that cerebrospinal fluid pulsation stress—cyclic pulsation stress—could promote the osteogenic and angiogenic abilities of rat MSCs, thereby promoting tissue-engineered laminae’s bone and blood vessel formation.

[Tissue and Cell] Using a gradient change of detergents and continuous agitation, scientists developed a unique technique to generate completely cell-free amnion and chorion scaffolds. The absence of cellular components and integrity of biological and mechanical cues within decellularized human amnion and chorion were evaluated and compared with fresh membranes.

[Journal of Bioenergetics and Biomembranes] The protein levels of osteogenesis-related genes, let-7i-5p, frizzled class receptor 4, Ki67, Wnt6 and β-catenin were measured by western blot assay. The levels of circ_FBLN1, FBLN1 mRNA and FZD4 mRNA were determined by quantitative real-time PCR assay.

[Molecular Medicine] Scientists summarize the effect and mechanism of lncRNA H19 on osteogenic differentiation of various stem cells reported in the published literatures. The role and mechanism of H19, H19 expression changes, effect of H19 on cell proliferation in osteogenic differentiation were respectively reviewed.

[Stem Cells International] Scientists explored the role of concentrated growth factor membranes in periodontal tissue regeneration mediated by human umbilical cord MSCs.

[Laboratory Investigation] Scientists explored the underlying mechanism of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1)-regulated angiogenesis during bone regeneration.