Cyclic Pulsation Stress Promotes Bone Formation of Tissue Engineered Laminae through the F-Actin/YAP-1/β-Catenin Signaling Axis

Researchers found that cerebrospinal fluid pulsation stress—cyclic pulsation stress—could promote the osteogenic and angiogenic abilities of rat MSCs, thereby promoting tissue-engineered laminae’s bone and blood vessel formation.