ovarian cancer

[International Journal of Oncology] A 3D organoid bioassay was utilized to test the efficacy of the combination therapy in a panel of seven epithelial ovarian cancer cell lines and ten platinum‑resistant primary patient tumor samples.

[Biochimie] Emerging evidence suggests that several microbial signatures are significantly associated with gynecological cancers.

[Frontiers in Bioengineering and Biotechnology] Researchers discuss applications to address the currently unmet need of developing physiologically relevant in vitro and ex vivo models of ovarian cancer for fundamental discovery science and personalized medicine approaches.

[Cancer Gene Therapy] Scientists observed the elevated expression of chemokine receptor 4 (CXCR4) in uveal melanoma (UM) patient liver tissues, and high CXCR4 expression in liver metastases of UM murine models, regardless of the expression levels in the primary tumors.

[npj Systems Biology and Applications] The authors used in vitro models to evaluate the transcriptional changes due to the presence of CTCFL, followed by a selection of gene candidates using de novo network enrichment analysis.

[PLoS One] Researchers presented novel biocompatible Polydimethylsiloxane-based micromechanical tweezers capable of the stiffness characterization and manipulation of hydrogel-based organoids.