pancreatic cells

[Oncogene] Researchers identified a key regulator of macropinocytosis for the survival of tumor cells in a low amino acid environment in pancreatic ductal adenocarcinoma.

[Cytotherapy] Scientists revealed that co-transplantation of umbilical cord mesenchymal stromal cella and autologous bone marrow mononuclear cells in patients with established type 1 diabetes was associated with reduced incidence of chronic diabetes complications.

[Oncogene] Scientists performed the molecular and histological assessment of patient-derived PanINs, tumor tissues and pancreas from mouse models with PDAC, where they noted marked upregulation of gastrokine proteins.

[Cell Death Discovery] Scientists investigated if TRAIL-R2 dependent signaling towards apoptosis can be induced in pancreatic β cells, whose loss by prolonged ER stress was associated with the onset of diabetes.

[Journal of Cachexia Sarcopenia and Muscle] Researchers assessed the functional, morphometric, biochemical, and molecular effects of P7C3 treatment in skeletal muscle of type 2 diabetic (db/db) mice.

[Science Advances] Nontransformed cells in tumors can help cancer cells overcome metabolic limitations, particularly in pancreatic cancer, where pancreatic stellate cells (PSCs) promote cancer cell proliferation and tumor growth.