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prostate cancer

LncRNA PCAT1 Activates SOX2 and Suppresses Radioimmune Responses via Regulating cGAS/STING Signaling in Non-Small Cell Lung Cancer

[Clinical and Translational Medicine] Investigators explored the impacts of prostate cancer-associated ncRNA transcripts 1 (PCAT1) on tumorigenesis and radioimmune responses and the underlying molecular mechanisms in NSCLC.

OCT1-Target Neural Gene PFN2 Promotes Tumor Growth in Androgen Receptor-Negative Prostate Cancer

[Scientific Reports] Scientists performed chromatin immunoprecipitation sequencing in patient-derived castration-resistant androgen receptor-negative prostate cancer cells to identify genes that are regulated by OCT1.

N6-Methyladenosine Demethylase FTO Suppressed Prostate Cancer Progression by Maintaining CLIC4 mRNA Stability

[Cell Death Discovery] Researchers suggested that fat mass and obesity-associated protein (FTO) suppressed prostate cancer proliferation and metastasis through reducing the degradation of CLIC4 mRNA in an m6A dependent manner.

Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers

[Molecular Cancer Research] Hypoxia increased androgen receptor expression and transcriptional activity in prostate cells in vitro.

SNAP25 Is a Potential Prognostic Biomarker for Prostate Cancer

[Cancer Cell International] The authors indicated a relationship between synaptosome associated protein 25 (SNAP25) expression and prostate cancer, demonstrating that SNAP25 was a potential prognostic biomarker due to its vital role in immune infiltration.

Fraxetin Down-Regulates Polo-Like Kinase 4 (PLK4) to Inhibit Proliferation, Migration and Invasion of Prostate Cancer Cells through the Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (Akt)...

[Bioengineered] The prostatic epithelial cell RWPE-1 and prostate cancer cell DU145 were exposed to Fraxetin to detect the changes in cell viability using cell counting kit-8 assay.

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