protein expression

[Biochemical Genetics] The authors investigated the role of circular RNA F-box and WD repeat domain containing 8 (circFBXW8) in NSCLC progression and the underlying mechanism.

[International Journal of Stem Cells] The protein expression of AKT, mTOR, p-AKT and p-mTOR was detected using western blot assay. The results showed that human umbilical cord mesenchymal stem cells treatment prominently promoted the glucocorticoid-induced the decrease of the collagen level and the increase of TRAP positive cells.

[Cell Reports] A single intravenous administration of mixture of nanoparticles and plasmid DNA expressing Cas9 controlled by CDH5 promoter and guide RNA induced highly efficient genome editing in endothelial cells of the vasculatures, including lung, heart, aorta, and peripheral vessels in adult mice.

[International Journal of Oncology] The expression and effect of miR‑1291 in colorectal cancer cells (CRC) was investigated. It was identified that miR‑1291 significantly suppressed the proliferation, invasion, cell mobility and colony formation of CRC cells.

[DNA and Cell Biology] Scientists analyzed the effects of Ginkgo biloba extract (GBE) administration on TET2 expression in human colorectal cancer (CRC). To investigate the expression profiles of TET2, GBE was used to treat CRC cells.

[Cell Death & Disease] Researchers reported that METTL14, a key component of N6-methyladenosine methylation, was functionally related to the inhibition of ARRDC4/ZEB1 signaling and to the consequent suppression of colorectal cancer metastasis.